International Conference on AI-ML-Systems is a new conference targeting research in the intersection of Systems Engineering and Artificial Intelligence and Machine Learning techniques. Through this conference, we plan to examine how immense strides in AI/ML techniques are made possible through advances in computational systems and how the use of AI/ML can help in the data-driven explorations of the design space of computational systems. We also investigate how new breeds of AI/ML systems enable new forms of socio-techno-economic systems and they in turn generate new requirements for research in AI/ML techniques.